Science

Tuesday, May 27, 2008

EU's satellite in orbit Lucia Hrusovska


One in 3 900 children in the US is born with Cystic Fibrosis. Over 8 000 people in UK are affected, and more than 30 000 Europeans have to live with this killing disease. Cystic Fibrosis is one of the most common life-threatening inherited diseases in the world. This week, scientists from UK seem to have finally overcome the major obstacle in their Gene Therapy research for this killing disease. Cystic Fibrosis is a hereditary disease that affects lungs, the exocrine glands, digestive system, liver and finally leads to a multisystem failure. It is caused by a single gene that controls the movement of salt in human body. People affected by Cystic Fibrosis suffer from liver and digestive disorders, repeated lung infections, respiratory failures and have to be on a strict diet and medication treatment. Despite all the cures, they often do not survive longer that to 36 years. Although there is no gene therapy approved for Cystic Fibrosis, it still holds promise as a potential remedy to cure the disease. Correcting the defective gene causing Cystic Fibrosis by replacing it by a healthy gene contained within a small circle of DNA called plasmid. Faulty lung may be healed by delivering enough plasmid to its cells and this should prevent 90% deaths caused by Cystic Fibrosis. In fact, gene therapy is a hope for most of diseases based on genetics such as cancer, heart disease, hereditary eye diseases. But science advances with failure as well as with success. More problem still have to be resolved, not only the ethical questions with religious basis, but also the negative after – effects on immune system, and disorders coming from gene mutation.

related story: http://www.medicalnewstoday.com/articles/105201.php

by Maria Vasilova
for PocketNews (http://pocketnews.tv)

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